Sunday, April 9, 2023

The Best Cooking Oil, - 25 Cancer Stem Cell Killing Foods, - Vitamin D Could Help Prevent Dementia, - Therapeutic Benefits of Direct Application of Vitamin C

 

THE GREATEST MEDICINE OF ALL… IS TEACHING PEOPLE HOW NOT TO NEED IT

IF YOU DON’T MAKE TIME FOR YOUR WELLNESS - YOU WILL BE FORCED TO MAKE TIME FOR YOUR ILLNESS!

 

Best Cooking Oil

This Is the #1 Cooking Oil a Registered Dietitian Says To Start Cooking With To Boost Your Longevity

Here's a juicy fact: According to Wendy Bazilian, DrPH, MA, RDN, a Doctor of Public Health and nutritionist and owner of Bazilian’s Health in San Diego, much as we love olive oil and avocado oil for their longevity-boosting benefits, chia oil might be an even better option—or at least one well-worth adding to your repertoire of favorite cooking oils. There's plenty of science to back Bazilian up, too: The benefits of consuming chia oil are well-researched, and it’s indeed packed with heart-healthy and anti-inflammatory properties, to name a few.

We caught up with Dr. Bazilian, who shared more about chia oil’s longevity-boosting nutrients, how to cook with it, and how it stacks up against other popular cooking oils on the market. The next time you’re shopping for groceries, we promise you’ll know exactly which type of chia oil to slide into your weekly meal prep routine.

The longevity-boosting benefits of chia oil

According to Dr. Bazilian, cold-pressed, unrefined chia oil—which has been used in many ancient civilizations for over 3,000 years—is an excellent source of the essential omega-3 fat ALA (alpha-linolenic acid), which is good for both your head and heart because it supports brain and cardiovascular functioning. “In fact, chia seeds contain the highest level of this omega-3 fat found in nature,” Dr. Bazilian says. And a little goes a long way: “A single teaspoon of chia oil is considered an ‘excellent source’ of this essential omega-3 and provides more than the daily adequate intake level established.”

“A single teaspoon of chia oil is considered an ‘excellent source’ of this essential omega-3 and provides more than the daily adequate intake level established.” —Wendy Bazilian, DrPH, MA, RDN

For context, Dr. Bazilian says that avocado oil and extra virgin olive oil have less than one percent ALA, and canola oil has less than nine percent of the omega-3 fatty acid. “Most cooking oils have higher percentages of monounsaturated fats and/or omega-6 polyunsaturated fats. Balancing out the types of unsaturated fats in your diet by adding omega-3s can be beneficial for health,” she says.

Dr. Bazilian also notes that this type of healthy fat not only imparts a delicious flavor to what you’re cooking, but it also provides a source of energy that helps make our cell membranes flexible and increase the absorption of other nutrients like fat-soluble vitamins A, E, D, and K.

To further reap the benefits of chia oil, Dr. Bazilian recommends pairing it with other nutrient-rich ingredients. “Fats, in general, can help with the absorption of certain phytonutrients, like carotenoids, which are found in carrots, leafy greens, avocados, and other vegetables. So when you eat chia oil with foods like spinach, carrots, or kale, your body will have an easier time absorbing the rich vitamin K and vitamin A—and your bones, skin, and immune system all benefit,” Dr. Bazilian says.

Growing evidence has also linked chia oil to anti-inflammatory properties related to staving off certain metabolic conditions like heart disease, dyslipidemia, and high blood pressure, to name a few. What’s more, chia is vegan-friendly, gluten-free, has no known allergenicity, and is high in protein and fiber. Generally speaking, chia oil is safe for most folks to consume regularly. However, those who take blood thinners or those with gallbladder-related illnesses should consult their physician before consuming.

Since chia oil has one of the highest smoke points of all plant-based cooking oils, it’s highly versatile and lends itself well to cooking in various ways. “Chia oil’s smoke point is 420°F, as verified by stability tests at various heat treatments,” Dr. Bazilian says. (For context, extra-virgin olive oil has a smoke point of 400°F, and avocado oil is 480°F.) Thus, chia oil is equally great for cooking at high heat as it is for serving at room temperature or cold, which offers high levels of important phytonutrients like phenolic acids, tocopherols, and phytosterols.

Dr. Bazilian recommends using chia oil to drizzle on top of dishes, using it to make dressings or marinades, or for sauteing or stir-frying ingredients. Additionally, thanks to its mild, delicate, and mostly neutral flavor, chia oil's ideal for baking or even adding to smoothies—which she says can elevate a recipe's silky, smooth mouthfeel. Plus, Dr. Bazilian recommends mixing and matching chia oil with other healthy cooking oils—like olive and avocado—to boost the nutrients in a recipe even more. “Often, I’ll use olive or avocado oil combined with chia oil,” she says.

The best chia oil options on the market

“Quality chia oil starts with a seed that is pure and high nutrition from the planting, growing, harvest, and processing, made with no chemicals solvents, enzymes or diluents,” Dr. Bazilian says. Chia oil made from high-quality seeds will have the highest amount of antioxidants and nutritional value. “Look for key indicators, such as cold-pressed and unrefined, or if the label mentions that it’s grown through regenerative agriculture.” This includes recommended brands like SOW’s unrefined, extra-virgin chia oil or Cucina & Amore’s chia oil, both available on Amazon.

 

25 Cancer Stem Cell Killing Foods Smarter Than Chemo & Radiation

Written By: Sayer Ji, Founder, GreenMedInfo LLC, 2023

An important scientific review identifies 25 of the top foods and herbs which kill the cancer stem cells at the root cause of cancer malignancy.

There are thousands of natural compounds that have been studied with demonstrable anti-cancer activity (check out over 600 on our cancer research database), but only a small subset of these have been proven to target and kill the cancer stem cells which lie at the root of cancer malignancy. Turmeric, for instance, we have featured a number of times for this "smart kill" property of targeting just the heart of cancerous tumors. More recently, ginger has been found in pre-clinical research to contain a compound up to 10,000 times more effective than the chemotherapy drug Taxol at killing breast cancer stem cells. Even common food like blueberry have special cancer killing properties, as discussed in a previous article: Research: Radiotherapy Causes Cancer, Blueberry Kills It.

A powerful study published in the journal Anticancer Research titled, "Natural Products That Target Cancer Stem Cells," has made our job much easier of identifying this special category of cancer killers by reviewing the extant literature on the topic and listing the top 25 substances in this category. They are listed here below, along with some of their commonly recognizable dietary sources:

  • Epigallocatechin-3-gallate (EGCG) - Green Tea
  • 6-Gingerol - Ginger
  • β-Carotene - Carrot, Leafy Greens
  • Baicalein - Chinese Skullcap
  • Curcumin - Turmeric
  • Cyclopamine - Corn Lilly [we do not suggest consuming this plant; this simply illustrates natural components exist that kill cancer stem cells]
  • Delphinidin - Blueberry, raspberrry
  • Flavonoids (Genistein) - Soy, red clover, coffee
  • Gossypol - Cottonseed [we do not suggest consuming this plant; this simply illustrates natural components exist that kill cancer stem cells]
  • Guggulsterone - Commiphora (myrrh tree)
  • Isothiocyanates - Cruciferous vegetables
  • Linalool - Mint
  • Lycopene - Grapefruit, tomato
  • Parthenolide - Feverfew
  • Perylill alcohol - Mint, cherry, lavender
  • Piperine - Black pepper
  • Platycodon saponin - Platycodon grandiflorum
  • Psoralidin - Psoralea corylilyfolia
  • Quercetin - Capers, onion
  • Resveratrol - Grapes, plums, berries
  • Salinomycin - Streptomyces albus
  • Silibinin - Milk Thistle
  • Ursolic acid - Thyme, basil, oregano
  • Vitamin D3 - Fish, egg yolk, beef, cod liver oil
  • Withaferin A - Withania somnifera (ashwaganda)

Why are these substances so important?

The primary reason why conventional chemotherapy and radiotherapy have failed to produce any significant improvements in cancer survival rates is because cancer stem cells are resistant to these interventions. In fact, chemotherapy and especially radiation are both capable of increasing the number and virulence of these cells in a tumor, while at the same time having the well-known side effect of further damaging the patient's immune system.

While the cancer industry is still very much resistant to incorporating the implications of these findings into their standard of care (which is highly unethical), there are an increasing number of health practitioners that will not turn their back on the truth and are very much interested in alternative ways to prevent and treat cancer using food and/or plant-based approaches.

The new study addresses the relevance of cancer stem cells as follows:

"The cancer stem cell model suggests that tumor initiation is governed by a small subset of distinct cells with stem-like character termed cancer stem cells (CSCs). CSCs possess properties of self-renewal and intrinsic survival mechanisms that contribute to resistance of tumors to most chemotherapeutic drugs. The failure to eradicate CSCs during the course of therapy is postulated to be the driving force for tumor recurrence and metastasis. Recent studies have focused on understanding the unique phenotypic properties of CSCs from various tumor types, as well as the signaling pathways that underlie self-renewal and drug resistance."

At present, the cancer industry has failed to produce a single drug that targets the cancer stem cell population of cells within a tumor, as confirmed by the study:

"If indeed the CSC response is a vital criterion for cancer treatment evaluation, there are still no drugs in clinical use that specifically target CSCs."

The ability to selectively target cancer cells, and cancer stem cells in particular, while leaving intact the non-tumor cells in tissue is extremely important. We have created a section on our database that indexes research on these substances and now includes sixty seven of them here. We are also building a section that collates research cancer stem cells, a topic will no doubt become a central part of the future of cancer treatment, assuming the priority is to actually alleviate suffering and not just make money off of patients.

 

Vitamin D Could Help Prevent Dementia, Study Finds

[Mar. 2, 2023:  Louise Vennells, University of Exeter]       

The team found that taking vitamin D was associated with living dementia-free for longer, and they also found 40 per cent fewer dementia diagnoses. Taking vitamin D supplements may help ward off dementia, according to a new, large-scale study.

Researchers at the University of Calgary’s Hotchkiss Brain Institute in Canada and the University of Exeter in the UK explored the relationship between vitamin D supplementation and dementia in more than 12,388 participants of the US National Alzheimer's Coordinating Center, who had a mean age of 71 and were dementia-free when they signed up. Of the group, 37 per cent (4,637) took vitamin D supplements.

In the study, published in Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, the team found that taking vitamin D was associated with living dementia-free for longer, and they also found 40 per cent fewer dementia diagnoses in the group who took supplements.

Across the entire sample, 2,696 participants progressed to dementia over ten years; amongst them, 2,017 (75%) had no exposure to vitamin D throughout all visits prior to dementia diagnosis, and 679 (25%) had baseline exposure.

Professor Zahinoor Ismail, of the University of Calgary and University of Exeter, who led the research, said: “We know that vitamin D has some effects in the brain that could have implications for reducing dementia, however so far, research has yielded conflicting results. Our findings give key insights into groups who might be specifically targeted for vitamin D supplementation. Overall, we found evidence to suggest that earlier supplementation might be particularly beneficial, before the onset of cognitive decline.”

While Vitamin D was effective in all groups, the team found that effects were significantly greater in females, compared to males. Similarly, effects were greater in people with normal cognition, compared to those who reported signs of mild cognitive impairment – changes to cognition which have been linked to a higher risk of dementia.

The effects of vitamin D were also significantly greater in people who did not carry the APOEe4 gene, known to present a higher risk for Alzheimer’s dementia, compared to non-carriers. The authors suggest that people who carry the APOEe4 gene absorb vitamin D better from their intestine, which might reduce the vitamin D supplementation effect. However, no blood levels were drawn to test this hypothesis.

Previous research has found that low levels of vitamin D are linked to higher dementia risk. Vitamin D is involved in the clearance of amyloid in the brain, the accumulation of which is one of the hallmarks of Alzheimer’s disease. Studies have also found that vitamin D may provide help to protect the brain against build-up of tau, another protein involved in the development of dementia.

Co-author Dr Byron Creese, at the University of Exeter, said: “Preventing dementia or even delaying its onset is vitally important given the growing numbers of people affected.  The link with vitamin D in this study suggests that taking vitamin D supplements may be beneficial in preventing or delaying dementia, but we now need clinical trials to confirm whether this is really the case.  The ongoing VitaMIND study at the University of Exeter is exploring this issue further by randomly assigning participants to either take vitamin D or placebo and examining changes in memory and thinking tests over time.”

The structure of APOE isoforms. APOE is a soluble secreted protein, with N-terminal and C-terminal domains linked by a central hinge region. (CREDIT: Frontiers)

The VitaMIND study is run via PROTECT, an online study open to people aged 40 and over. In PROTECT annual questionnaires on detailed lifestyle factors combine with cognitive testing, to determine what keeps the brain sharp in later life. 

The study is entitled ‘Sex, cognitive status, and APOE effects for vitamin D exposure and incident dementia’, and is published in Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring.

 

Therapeutic Benefits of Direct Application of Vitamin C

Orthomolecular Medicine News Service, April 9, 2023

Physicians' use of topical ascorbate began over 50 years ago

OMNS (April 9, 2023) I kept wondering where the pustulous rash on my wrists and between my fingers was coming from. It appeared at the end of an afternoon of working in my back yard vegetable gardens. Suspecting some poison plants to be out there somewhere, I resolved to pinpoint and eradicate them. But my immediate need was to stop the really annoying itching. Necessity being the parent of invention, I decided to try topical application of vitamin C. It was quick and easy: I simply took a half teaspoon of ascorbic acid powder and added drops of water until it formed a paste. Generously applied to the rash, it relieved the itch in less than 15 minutes. A day or so of twice-daily repetition and the rash was gone. I learned that the offending plants in my yard were belladonna and poison sumac. I have also seen this work on poison oak and poison ivy. And I am now more diligent in wearing work gloves.

The general idea of using vitamin C topically did not come to me out of nowhere. Back in 1984, Robert F. Cathcart III, MD, published on how to make what he simply called "C-paste." He used it for herpes simplex lesions and early Kaposi's lesions. "C-paste is made with either ascorbic acid or sodium ascorbate and water applied directly to the skin and covered with a bandage. Frequently, one application will suffice for herpes. . . Frequently, applications to intact skin where the patient perceives an outbreak is about to occur will completely abort the attack. Several applications may be necessary to penetrate through the intact skin."

Topical vitamin C is a remarkable and versatile antiviral. Vitamin C paste applied directly to HSV or HPV lesions may make a visible difference, sometimes overnight. It is also effective on warts, which are viral.  If ascorbic acid C stings, one may use sodium ascorbate instead of ascorbic acid. I have seen both to work.

All this apparent antiviral property of concentrated vitamin C was an odd companion to the earlier antitoxic property I had experienced.

Preparation of a water-based vitamin C paste is simple. Slowly add a small amount of water to about half a teaspoon of vitamin C powder. Use just enough water to wet down the vitamin C. Using less water will make a thicker paste. Application with the fingertip or a cotton swab, several times daily, is easy. The water will evaporate in a few minutes and leave a plainly visible but temporary coat of vitamin C crystals on the skin.

It was soon to get even more interesting: I learned that vitamin C had been used to actually destroy cancer cells. How well it does so is easily and visibly demonstrated by twice-daily topical application directly onto basal cell skin carcinomas. There is no localized dose higher than that achieved by direct application.

The use of topical vitamin C to kill basal cell carcinoma has been known at least since 1971. Frederick R. Klenner, MD, wrote: "We have removed several small basal cell epithelioma with a 30 percent ointment" of vitamin C.

One person, who reported that a 2mm diameter spot on the nose would not heal for months, had it disappear within a week with twice-daily concentrated vitamin C applications. Another patient reported that after dermatologist-diagnosed multiple spots of basal cell carcinoma were coated with vitamin C, the spots fell off within two weeks.

Common sense caution: First have your physician diagnose any suspected cancer-like blemish. Basal cell carcinomas are slow growing and it is rare for them to metastasize. This provides an opportunity for a therapeutic trial of vitamin C, provided one has proper medical diagnosis and follow-up. But malignant melanoma, for example, is fast-spreading and most definitely not to be home-treated.

Broad-spectrum utility of a pharmaceutical drug is generally lauded as a boon to humanity. Yet a vitamin demonstrating wide-ranging properties as an antitoxic, antiviral, anti-cancer, and anti-hemorrhagic agent has been largely dismissed by the medical profession.

Andrew W. Saul is in his 20th year as Editor-in-Chief of the Orthomolecular Medicine News Service. He is neither a virologist nor a physician. He is author or coauthor of a dozen books and has taught clinical nutrition and cell biology at the university level. Work directly with your own healthcare provider on any health issue.)

Until next time, stay healthy and happy

JD Roma

 

The information on this blog is provided for educational purposes only. It is not a substitute for professional medical care, and medical advice and services are not being offered. If you have, or suspect you have, a health problem you should consult your physician.

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