Tuesday, July 9, 2019

New Study Results, Statins Can Cause ALS, LDL-Cholesterol Does Not Predict Heart Disease Risk



"THE GREATEST MEDICINE OF ALL Is Teaching People How Not To Need It"

Updates on Interesting New Studies

Curcumin Improves Inflammation and Cholesterol in Obese Men

Obesity increases chances for heart problems, which can begin with systemic inflammation and imbalanced lipids. In this study, 22 men, aged 18 to 35, with body mass index scores of at least
30, took fenugreek fiber alone (placebo), or along with 500 mg of curcumin enhanced
with a small amount of fenugreek to enhance absorption per day. The men had no history of high blood pressure or blood sugar, heart attack, or diabetes.

After 12 weeks, levels of homocysteine, an inflammatory factor in heart disease, declined by 29.5 percent for the curcumin-fenugreek group while increasing 25.3 percent for the fenugreek placebo alone. Levels of HDL, the good cholesterol that protects the heart, increased 33.8 percent for the curcumin-fenugreek group while declining 20.2 percent for the fenugreek placebo alone.
Reference: Nutrition; June 2019, Vol. 62, 135-139.

Fruits and Veggies for Cognition

This long-term study measured the diets of 27,842 men, average age 51, over a 20-year period. Every
four years, the men reported the previous year's diet and any changes in memory and cognition. Doctors assessed cognition at average age 73.

Overall, men who consumed the most vegetables were 34 percent less likely to have developed cognitive decline compared to men who got the least. Those who drank orange juice daily were 47 percent less likely compared to those who drank OJ less than once a month, and eating more fruit was also beneficial. Leafy greens, dark orange and red vegetables, and berry fruits had the strongest links to good cognition.
Reference: Neurology; January 01,

Vitamin D may reduce chronic obstructive pulmonary disease (COPD)

In chronic obstructive pulmonary disease (COPD), lt is difficult to breathe fully, with symptoms at times becoming more acute, called exacerbations, which require medication. In this review of three vitamin D studies, covering 469 men and women, aged 40 to 86, with moderate to very severe COPD, doctors administered a placebo or doses of vitamin D from 36,000 IU to 100,000 IU per month.

The primary purpose of the studies was to measure the rate of COPD exacerbations that required treatment with corticosteroids, antibiotics, or both. Overall, while there were no changes in those
who began the study with vitamin D levels greater than 25 nanomole per liter of blood, or 10 nanograms per milliliter of blood, those who began the study with lower levels of vitamin D and who took vitamin D during the study saw rates of exacerbations requiring medication drop by 45 percent.
Reference: Thorax 2019: 74: 337-345.

Aged Garlic Extract Reduced Gingivitis

Gingivitis is a common type of gum disease that develops when bacterial plaque builds up along the gum line and in between teeth. In this study, 134 men and women, average age 33, with gingivitis, took a placebo or a daily dose of aged garlic extract (Kyolic'"). Dental examiners measured the number of bleeding sites and assessed gum health at the start of the study, and monthly for four more months.

Using a standard index of clinical gingival symptoms, while the placebo group had not improved, those taking aged garlic extract saw significant reductions in inflammation, and in the number and severity of bleeding sites, beginning at month one and continuing through four months.

When plaque builds up, it triggers an immune response, which, if left unchecked, can destroy gum tissue. Doctors said garlic helps control bad bacteria and promotes good bacteria, keeping a healthy balance in the mouth.
Reference: Journal of Clinical Dentistry; 2018, Vol. 29, No.2, 52-56.

Aged Garlic Extract Lowers High Blood Pressure

Controlling high blood pressure helps protect the heart. In this study, 49 adults with uncontrolled hIgh blood pressure took a placebo or a daily dose of aged garlic extract (Kyolic'").

After 12 weeks, those taking aged garlic extract saw an average reduction in systolic blood pressure of 10 mmHg and 5.4 mmHg in diastolic blood pressure, compared to placebo. Those taking garlic also saw lower pressure in the central blood vessels and arteries that carry blood to and from the heart, as well as more flexible arteries. Also, those taking garlic had measurable increases in the gut probiotics lactobacillus and clostridia, signaling a more balanced microbiome.

Reviewing the results, doctors said aged garlic extract is safe for treating high blood pressure, with multiple benefits for heart and circulatory health.

Reference: Frontiers in Nutrition; December 2018, Vol. 5, No. 122, Published Online.


Vitamin D Deficiency and Schizophrenia

In the womb, babies must rely completely on mothers' stores of vitamin D and, in new findings, those born deficient in Vitamin D are more likely to develop schizophrenia later in life. In this study, doctors measured vitamin D levels at the time of birth in 2,602 newborns that went on to develop schizophrenia as young adults.

Those with the lowest levels of vitamin D at birth-less than 20.4 nanomole per liter of blood, or 8.16 nanograms per milliliter-were 44 percent more likely to develop schizophrenia as young adults compared to those born with normal vitamin D levels.

Reference: Nature - Scientific Reports; December 2018, Vol. 8, Article No. 17692.


The probiotic lactobacillus; may help control blood sugar in type 2 diabetes

Recent research suggests a balanced gut microbiome is critical maintaining health and managing chronic conditions such as type 2 diabetes. In this study, 40 normal weight to obese adults, aged 30 to 50, with type 2 diabetes, took a placebo or 100-million colony- forming units of the probiotic lactobacillus casei per day.

After eight weeks, for those taking probiotics, fasting blood sugar levels declined to 135.84 milligrams per deciliter of blood from 164.20, while increasing slightly for placebo. Long-term average blood sugar levels, or HbAIC, declined to 6.84 from 7.30 while increasing for placebo. Insulin levels and insulin resistance both declined for probiotics while increasing for placebo. Weight, body mass index scores, and waist circumference also improved for probiotics.
Reference: Iranian Biomedical Journal; 2019, Vol. 23, No.1, 68-77.


Could This Vitamin SAVE You From Parkinson's?

When you're dealing with Parkinson's disease, you know you're racing against time. You're hoping to fight the tremors... stiffness... pain... and psychological effects for as long as you can, before they destroy your quality of life.

But there may be an easy way to keep Parkinson's in check -- and give yourself some precious extra years of good living. It's not a drug... in fact, it's a simple vitamin you can get anywhere.

A recent study found that vitamin B12 can prevent the formation of clumps in your brain associated with Parkinson's disease... even destroy them. These clumps are known as alpha-synuclein aggregates, and they're toxic.

They mess with your brain health and can trigger the onset and progression of Parkinson's. Even Big Pharma knows this. They've been working to develop drugs that inhibit these alpha-synuclein aggregates.

But vitamin B12 is a much easier and safer strategy than anything the drug companies will come up with. This shouldn't come as a big surprise. The entire spectrum of B vitamins are crucial to neurological processes and keeping your brain sharp.

And the sad thing is, most people in the United States are deficient in vitamin B12.

Thankfully, there are plenty of food sources rich in this vitamin... beef, liver, chicken, seafood, eggs, and various dairy products are chock full of vitamin B12. And you can buy B12 (or B complex) supplements for pennies a day. B vitamins like B12 aren't just an easy way to fight back against your Parkinson's symptoms. These all-natural vitamins may just give you the greatest gifts of all. More time... and a better quality of life.


New drug danger discovered: Statins found to cause ALS, a fatal nervous system disorder

Many people take statins with the aim of improving their health, but these drugs come with so many side effects that they’re often not worth taking. Long under fire for their lack of results and their role in raising the risk of diabetes, yet another reason has emerged for avoiding these drugs: They can cause the deadly disorder ALS.

ALS, which stands for amyotrophic lateral sclerosis, is a nervous system disorder that causes progressive muscle strength loss that is irreversible. Also known as Lou Gehrig’s disease, it can cause nerve cells within the spinal cord and brain that control your voluntary muscles to die. It may start with weakness in one leg or arm and speech changes before leading to muscle twitching and eventually preventing people from moving, speaking, eating and breathing. There is no cure, and the disease is fatal.

According to a new study that was published in the Drug Safety journal, statins could be one of the driving factors behind sporadic cases of ALS, which account for roughly nine out of ten ALS diagnoses. In the study, researchers looked at the reporting odds ratio, or ROR, of statins in relation to ALS and ALS-like symptoms. An ROR of 6 or greater generally suggests probable cause.

While the RORs for ALS were considered elevated for all of the statins studied, they discovered that lipophilic statins like Lovastatin (Altoprev) had an alarmingly high ROR of 107. Meanwhile, the ROR for Simvastatin (Zocor) was 23, while that of the popular statin Atorvastatin (Lipitor) was 17 and Rosuvastatin (Crestor) was 9.09. The researchers concluded that there is indeed a concerning connection that warrants further exploration.

Statins have lots of side effects, few benefits

If you take statins, ALS isn’t the only medical problem you have to worry about. They’ve also been linked to a higher risk of heart disease and memory loss. The most common side effects include cognitive problems, fatigue and muscle symptoms, while some people note aggression, higher irritability, and numbness or tingling in their extremities. And while they are intended to reduce the risk of suffering an ischemic stroke, they can raise the risk of hemorrhagic strokes.

Statins have also been shown to double the risk of developing diabetes. The risk is even higher among post-menopausal women, with one large study of more than 150,000 women showing that this group’s risk of diabetes rises by 71 percent by taking statins.

Statins are a huge moneymaker for doctors and pharmaceutical companies, so it’s unlikely that prescriptions will slow down any time soon. Thankfully, many people can avoid them by making lifestyle changes that will improve their health and bring their cholesterol to healthier levels. While it’s not quite as easy as taking a pill, improving your diet and getting regular exercise won’t raise your risk of ALS or any other illness – in fact, it will have the opposite effect.

The first step is adding more foods to your diet that are known to fight cholesterol. Focus on getting plenty of omega 3 fatty acids and fiber, and eat foods like oats, fish and garlic. Try to increase your physical activity levels, whether you’re going from being sedentary to taking a few slow strolls round the block after dinner each week or turning a couple of your weekly jogs into runs. No matter what you’re currently doing, there is a way to raise the intensity.

With nearly one out of every four people in the U.S. over the age of 45 taking statins, it’s important that everyone is aware of the risks posed these drugs and the safer alternatives for lowering your cholesterol and protecting your heart health naturally.



International Study Confirms LDL-Cholesterol Doesn't Predict Heart Disease Risk; Statin Drugs Probably Useless
Article by GreenMedInfo LLC, 2019

A recent international study published in the highest ranking cardiovascular journal in the world confirms what we’ve been saying at GreenMedInfo for over a decade: LDL cholesterol is not an accurate predictor of future cardiovascular events and is not a good indicator of the underlying causes of heart disease -- the implication of which is statin drugs are useless at best, and cardiotoxic at worst.

Published in European Heart Journal and titled, “Development and validation of a ceramide- and phospholipid-based cardiovascular risk estimation score for coronary artery disease patients," the study sought to identify whether LDL-cholesterol or a new class of blood lipids known as ceramide lipids are best in predicting heart attack risk in coronary heart disease (CHD) patients.

The study found that despite assumptions that all CHD patients have equivalent cardiovascular disease risk, the 10-year cardiovascular disease risk of a CHD patient varies from 5% to over 20%.

Presently, the primary tool used to identify cardiovascular disease risk, and to reduce it, is LDL cholesterol and LDL cholesterol suppressing drugs, respectively. LDL cholesterol was not found to be effective in identifying who are the more high risk patients for cardiovascular death or heart attack:

Given the fact that cardiovascular diseases are the leading cause of death worldwide, misidentifying LDL cholesterol as the primary cause of heart disease, and then promoting LDL cholesterol suppression therapies like statin drugs as a solution, is a tragic mistake. Especially given that statin drugs have over 300 adverse effects that have been identified in the biomedical literature, including profound cardiotoxicity. 

The study, therefore, indicates that certain dietary practices, such as the consumption of omega-3 fatty acids, may positively contribute towards ceramide profiles indicative of lower cardiovascular disease risk, as identified through the CERT2 risk statification test. Given the robust literature on the therapeutic benefit of fish oil (one of the only sources of DHA in the human diet today) for cardiovascular health, could this indicate fish oil may provide a natural alternative to statin drugs?

Interestingly, we've reported previously on how statin drugs may actually interfere with the cardiotherapeutic properties of fish oil, as well as how statin drug manufacturers like Pfizer have funded studies attempting to discredit fish oil's heart benefits. Given the latest research, and the well-known problems with the statin-based approach to preventing heart disease, one thing is true, if LDL cholesterol is not an accurate surrogate marker of cardiovascular disease risk, then the conventional statin-based standard of care is no longer supported by the scientific evidence.

Until next time, stay healthy and happy

JD Roma


The information on this blog is provided for educational purposes only. It is not a substitute for professional medical care, and medical advice and services are not being offered. If you have, or suspect you have, a health problem you should consult your physician (preferably a Naturopath).

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